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Sorriso Pharmaceuticals Launches with $31 Million to Develop Novel Class of Orally Delivered Cytokine Antibodies to Treat Inflammatory Conditions

December 27, 2021

Sorriso Pharmaceuticals announced the company has closed on a $31 million Series A financing. The round was co-led by New Enterprise Associates (NEA), and Arix Bioscience plc. The new funding will be used to advance its pipeline of novel oral antibodies to address unmet needs in immune- mediated diseases.

Sorriso Pharmaceuticals is a biotechnology company advancing a pipeline of disease-modifying antibodies for the treatment of inflammatory disease, including Crohn’s disease and ulcerative colitis. The Sorriso platform generates potent antibodies that can be delivered orally and are designed to maintain activity throughout the intestinal system.  The lead program is SOR102, in development for the treatment of inflammatory bowel disease (IBD).  SOR102 simultaneously inhibits TNFa and IL-23, two clinically validated drivers of IBD. This unique approach combines the strong clinical impact of injectable antibody therapeutics with the benefits of oral administration, resulting in targeted activity, negligible systemic exposure, and minimal immunogenicity. “Current systemic IBD therapies are suboptimal and have a greater risk of immunosuppression,” said Ciara Kennedy, president, and CEO of Sorriso Pharmaceuticals. “SOR102 has the potential to transform IBD therapy with minimal systemic exposure.”

In association with the financing, Ed Mathers, general partner at NEA, and Mark Chin, managing director at Arix Bioscience have been appointed to Sorriso’s board of directors.

“We are excited to partner with Sorriso’s experienced, dedicated management team to support their future growth plans,” said Ed Mathers. “Sorriso is developing a promising new platform for orally available biological treatments with the potential to significantly relieve treatment burden for countless patients who rely on drugs that can only be administered via injection.”


For more information on Sorriso, please contact:
Sorriso Pharmaceuticals, Inc.