The study is being led by professor of oral biology, Dr. David Wong, from the UCLA School of Dentistry, a research-intensive dental school and the lead U.S. research site for the study.

“At Spectrum Solutions, we are proud to sponsor Dr. Wong and UCLA in this exciting research project to unlock and harness the potential of saliva as a primary diagnostic resource to combat and improve the lives and wellbeing of people around the world,” said Stephen Fanning, President and CEO of Spectrum Solutions. “We look forward to working with the innovative researchers at UCLA and pledge our full support.”

“Saliva-based liquid biopsy ctDNA detection can be used to not only provide an accurate cancer diagnosis, but additionally track the actionable mutations, monitor a response to treatments, and assess the emergence of drug resistance,” Dr. Wong said. “This study’s non-invasive use of saliva for the analysis of ctDNA will prove to overcome current limitations, provide procedures that improve detection sensitivity, and offer significant clinical impact on early detection, risk assessment, screening, diagnosis, and personalized/precision medicine.”

The research study will compare saliva and plasma samples from NSCLC patients to identify usctDNA molecules in saliva and use special extraction methods to improve overall sensitivity of current liquid biopsy procedures.